InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ATP5J2

Summary

InnateDB Gene

IDBG-640797.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP5J2

Gene Name

ATP synthase subunit f, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002094

Encoded Proteins

IDBP-693093

ATP synthase subunit f, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241468:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene. [provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:37494182-37499276

Strand

Forward strand

Band

Transcripts

ENSBTAT00000043764

ENSBTAP00000041308

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006754	ATP biosynthetic process
GO:0006810	transport
GO:0006811	ion transport
GO:0015992	proton transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
GO:0070062	extracellular vesicular exosome