Version 5.4
Mus musculus Gene: Dtl
Summary
InnateDB Gene IDBG-208766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dtl
Gene Name denticleless homolog (Drosophila)
Synonyms 2810047L02Rik; 5730564G15Rik; Ramp
Species Mus musculus
Ensembl Gene ENSMUSG00000037474
Encoded Proteins
IDBP-208768
denticleless homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143476:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:191537365-191575534
Strand Reverse strand
Band H6
Transcripts
ENSMUST00000027933 ENSMUSP00000027933
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0006260 DNA replication
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0006974 cellular response to DNA damage stimulus
GO:0009411 response to UV
GO:0019985 translesion synthesis
GO:0031572 G2 DNA damage checkpoint
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 Cul4B-RING E3 ubiquitin ligase complex
GO:0031965 nuclear membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143476
View Gene Order
ENSBTAG00000018142
Not yet available
Cross-References
SwissProt Q3TLR7
TrEMBL
UniProt Splice Variant
Entrez Gene 76843
UniGene Mm.412729
RefSeq NM_029766
OMIM
CCDS CCDS15621
HPRD
IMGT
MGI ID MGI:1924093
MGI Symbol Dtl
EMBL AB095735 AB095736 AK012919 AK054412 AK133177 AK161401 AK166351 BC060208
GenPept BAB28549 BAC35769 BAC76404 BAC76405 BAE21543 BAE36376 BAE38725
RNA Seq Atlas 76843

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca