Version 5.4
Mus musculus Gene: Arhgap17
Summary
InnateDB Gene IDBG-209112.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap17
Gene Name Rho GTPase activating protein 17
Synonyms 5730403H17Rik; Nadrin; Nadrin2; Rich1; Wbp15
Species Mus musculus
Ensembl Gene ENSMUSG00000030766
Encoded Proteins
IDBP-209114
Rho GTPase activating protein 17
IDBP-268749
Rho GTPase activating protein 17
IDBP-621822
Rho GTPase activating protein 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140750:
RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:123279150-123369915
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000098060 ENSMUSP00000095668
ENSMUST00000106442 ENSMUSP00000102050
ENSMUST00000167309 ENSMUSP00000128447
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005923 tight junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140750
View Gene Order
ENSBTAG00000020043
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
rac1_reg_pathway
Regulation of RAC1 activity
cdc42_reg_pathway
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL E9QAJ9
UniProt Splice Variant
Entrez Gene 70497
UniGene Mm.472252
RefSeq NM_001122640 NM_001122642 NM_001122641 NM_001122643 NM_144529 XM_006508202
OMIM
CCDS CCDS52390 CCDS52388 CCDS52389
HPRD
IMGT
MGI ID MGI:1917747
MGI Symbol Arhgap17
EMBL AC121956 AC138364
GenPept
RNA Seq Atlas 70497

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca