Version 5.4
Mus musculus Gene: Lcmt1
Summary
InnateDB Gene IDBG-209140.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lcmt1
Gene Name leucine carboxyl methyltransferase 1
Synonyms AL033290; Lcmt; LCMT-1
Species Mus musculus
Ensembl Gene ENSMUSG00000030763
Encoded Proteins
IDBP-209142
leucine carboxyl methyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205629:
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:123377982-123430358
Strand Forward strand
Band F3
Transcripts
ENSMUST00000033025 ENSMUSP00000033025
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003880 protein C-terminal carboxyl O-methyltransferase activity
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
Biological Process
GO:0006479 protein methylation
GO:0006481 C-terminal protein methylation
GO:0010906 regulation of glucose metabolic process
GO:0031333 negative regulation of protein complex assembly
GO:0032259 methylation
GO:0042981 regulation of apoptotic process
GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000205629
View Gene Order
ENSBTAG00000013169
Not yet available
Cross-References
SwissProt
TrEMBL A2RTH5 Q78K29
UniProt Splice Variant
Entrez Gene 30949
UniGene
RefSeq NM_025304
OMIM
CCDS CCDS40118
HPRD
IMGT
MGI ID MGI:1353593
MGI Symbol Lcmt1
EMBL AC121956 BC010316 BC132507 BC132509 CH466531
GenPept AAH10316 AAI32508 AAI32510 EDL17309
RNA Seq Atlas 30949

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca