Mus musculus Gene: Srxn1 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-209605.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Srxn1 | ||||||||
Gene Name | sulfiredoxin 1 homolog (S. cerevisiae) | ||||||||
Synonyms | 1700127B04Rik; AI854065; AW488194; Npn3; Srx; Srx1; TX01 | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000032802 | ||||||||
Encoded Proteins |
sulfiredoxin 1 homolog (S. cerevisiae)
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
InnateDB Annotation | |||||||||
Summary |
Srxn1 is transcriptionally regulated by Nfe2l2 in immunostimulated primary macrophages that produce both reactive oxygen species and nitric oxide. The nitric oxide/Nfe2l2/Srxn1 pathway participates in the maintenance of redox homeostasis in cytokine-activated macrophages and other inflammatory settings.
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InnateDB Annotation from Orthologs | |||||||||
Summary |
[Homo sapiens] SRXN1 is transcriptionally regulated by NFE2L2 in immunostimulated primary macrophages that produce both reactive oxygen species and nitric oxide. The nitric oxide/NFE2L2/SRXN1 pathway participates in the maintenance of redox homeostasis in cytokine-activated macrophages and other inflammatory settings. (Demonstrated in murine model)
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Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 2:152105516-152111376 | ||||||||
Strand | Forward strand | ||||||||
Band | G3 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.218639 | ||||||||
RefSeq | NM_029688 | ||||||||
OMIM | |||||||||
CCDS | CCDS16877 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||