Version 5.4
Mus musculus Gene: Tpx2
Summary
InnateDB Gene IDBG-209892.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tpx2
Gene Name TPX2, microtubule-associated protein homolog (Xenopus laevis)
Synonyms 2610005B21Rik; DIL2; p100; REPP86
Species Mus musculus
Ensembl Gene ENSMUSG00000027469
Encoded Proteins
IDBP-209894
TPX2, microtubule-associated protein homolog (Xenopus laevis)
IDBP-261579
TPX2, microtubule-associated protein homolog (Xenopus laevis)
IDBP-622066
TPX2, microtubule-associated protein homolog (Xenopus laevis)
IDBP-718281
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088325:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152847964-152895321
Strand Forward strand
Band H1
Transcripts
ENSMUST00000028969 ENSMUSP00000028969
ENSMUST00000109816 ENSMUSP00000105441
ENSMUST00000136407
ENSMUST00000144848
ENSMUST00000143740
ENSMUST00000164120 ENSMUSP00000128888
ENSMUST00000178997 ENSMUSP00000136457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0007067 mitotic nuclear division
GO:0032147 activation of protein kinase activity
GO:0060236 regulation of mitotic spindle organization
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0043203 axon hillock
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000088325
View Gene Order
ENSBTAG00000018775
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt A2APB8
TrEMBL Q9CT36
UniProt Splice Variant
Entrez Gene 72119
UniGene Mm.407737
RefSeq NM_001141975 NM_001141976 NM_001141978 NM_001141977 NM_028109 XM_006500213 XM_006500214 XM_006500215
OMIM
CCDS CCDS16900
HPRD
IMGT
MGI ID MGI:1919369
MGI Symbol Tpx2
EMBL AK011311 AK153957 AL833801 BC060619 CH466551
GenPept AAH60619 BAB27537 BAE32280 CAM23677 EDL05994
RNA Seq Atlas 72119

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca