Version 5.4
Mus musculus Gene: Sez6l2
Summary
InnateDB Gene IDBG-209972.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sez6l2
Gene Name seizure related 6 homolog like 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000030683
Encoded Proteins
IDBP-268981
seizure related 6 homolog like 2
IDBP-268983
seizure related 6 homolog like 2
IDBP-268985
seizure related 6 homolog like 2
IDBP-534205
seizure related 6 homolog like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174938:
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:126950563-126970606
Strand Forward strand
Band F3
Transcripts
ENSMUST00000106335 ENSMUSP00000101942
ENSMUST00000106333 ENSMUSP00000101940
ENSMUST00000106332 ENSMUSP00000101939
ENSMUST00000146017 ENSMUSP00000115905
ENSMUST00000125669
ENSMUST00000134471
ENSMUST00000155138
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008344 adult locomotory behavior
GO:0021680 cerebellar Purkinje cell layer development
GO:0060074 synapse maturation
GO:0090036 regulation of protein kinase C signaling
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174938
View Gene Order
ENSBTAG00000007955
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.283926
RefSeq NM_001252566 NM_001252567 NM_144926
OMIM
CCDS CCDS40135 CCDS57585 CCDS57586
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca