Version 5.4
Bos taurus Gene: SEZ6L2
Summary
InnateDB Gene IDBG-639277.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEZ6L2
Gene Name Seizure 6-like protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007955
Encoded Proteins
IDBP-691420
Seizure 6-like protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174938:
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:26620088-26640306
Strand Forward strand
Band
Transcripts
ENSBTAT00000010460 ENSBTAP00000010460
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008344 adult locomotory behavior
GO:0021680 cerebellar Purkinje cell layer development
GO:0060074 synapse maturation
GO:0090036 regulation of protein kinase C signaling
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000174938
View Gene Order
ENSMUSG00000030683
View Gene Order
Cross-References
SwissProt Q29RN8
TrEMBL
UniProt Splice Variant
Entrez Gene 505735
UniGene Bt.46577
RefSeq NM_001045927 XM_005224855
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114092
GenPept AAI14093
RNA Seq Atlas 505735

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca