Version 5.4
Mus musculus Gene: Osbpl7
Summary
InnateDB Gene IDBG-210135.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Osbpl7
Gene Name oxysterol binding protein-like 7
Synonyms 4933437E18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000038534
Encoded Proteins
IDBP-210139
oxysterol binding protein-like 7
IDBP-622562
oxysterol binding protein-like 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006025:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:97050628-97068904
Strand Forward strand
Band D
Transcripts
ENSMUST00000090020 ENSMUSP00000087474
ENSMUST00000154084
ENSMUST00000142399
ENSMUST00000142406
ENSMUST00000143360
ENSMUST00000168565 ENSMUSP00000126902
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0071397 cellular response to cholesterol
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0005776 autophagic vacuole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000006025
View Gene Order
ENSBTAG00000013523
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.190450
RefSeq NM_001081434
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca