Homo sapiens Gene: OSBPL7
Summary
InnateDB Gene IDBG-56184.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL7
Gene Name oxysterol binding protein-like 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000006025
Encoded Proteins
oxysterol binding protein-like 7
oxysterol binding protein-like 7
oxysterol binding protein-like 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:47807372-47821834
Strand Reverse strand
Band q21.32
Transcripts
ENST00000007414 ENSP00000007414
ENST00000392507 ENSP00000376295
ENST00000579728 ENSP00000463599
ENST00000584698
ENST00000580226
ENST00000578461 ENSP00000464624
ENST00000580140
ENST00000585051
ENST00000580808
ENST00000583167
ENST00000613735 ENSP00000479827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0071397 cellular response to cholesterol
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0005776 autophagic vacuole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.463320
RefSeq NM_145798 XM_005257010
HUGO
OMIM
CCDS CCDS11515
HPRD 09477
IMGT
EMBL
GenPept
RNA Seq Atlas