Version 5.4
Mus musculus Gene: Tbkbp1
Summary
InnateDB Gene IDBG-210156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbkbp1
Gene Name TBK1 binding protein 1
Synonyms 3110043L15Rik; ProSAPiP2; SINTBAD
Species Mus musculus
Ensembl Gene ENSMUSG00000038517
Encoded Proteins
IDBP-210160
TBK1 binding protein 1
IDBP-266289
TBK1 binding protein 1
IDBP-266291
TBK1 binding protein 1
IDBP-266293
TBK1 binding protein 1
IDBP-400074
TBK1 binding protein 1
IDBP-540316
TBK1 binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 17568778
[Homo sapiens] A novel component of innate antiviral immunity, it shares a TBK1-binding domain with AZI2 and TANK
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198933:
TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:97136171-97151495
Strand Reverse strand
Band D
Transcripts
ENSMUST00000066078 ENSMUSP00000065461
ENSMUST00000107615 ENSMUSP00000103240
ENSMUST00000107614 ENSMUSP00000103239
ENSMUST00000107613 ENSMUSP00000103238
ENSMUST00000118375 ENSMUSP00000112396
ENSMUST00000146374 ENSMUSP00000114460
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0045087 innate immune response
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198933
View Gene Order
ENSBTAG00000011280
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04622
RIG-I-like receptor signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
hsa04622
RIG-I-like receptor signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27882
RefSeq NM_198100 XM_006534335 XM_006534336 XM_006534337
OMIM
CCDS CCDS48895
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca