Version 5.4
Mus musculus Gene: Tacc2
Summary
InnateDB Gene IDBG-210815.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tacc2
Gene Name transforming, acidic coiled-coil containing protein 2
Synonyms mKIAA4180
Species Mus musculus
Ensembl Gene ENSMUSG00000030852
Encoded Proteins
IDBP-210817
transforming, acidic coiled-coil containing protein 2
IDBP-210819
transforming, acidic coiled-coil containing protein 2
IDBP-210821
transforming, acidic coiled-coil containing protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:130577484-130764784
Strand Forward strand
Band F3
Transcripts
ENSMUST00000084513 ENSMUSP00000081561
ENSMUST00000059145 ENSMUSP00000061242
ENSMUST00000033141 ENSMUSP00000033141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019904 protein domain specific binding
GO:0035257 nuclear hormone receptor binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0008283 cell proliferation
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0022027 interkinetic nuclear migration
GO:0030953 astral microtubule organization
GO:0032886 regulation of microtubule-based process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138162
View Gene Order
ENSBTAG00000010786
Not yet available
Cross-References
SwissProt
TrEMBL E9Q9Z4
UniProt Splice Variant
Entrez Gene 57752
UniGene Mm.86322
RefSeq NM_206856 NM_001004468 NM_021314
OMIM
CCDS CCDS21904 CCDS21903 CCDS21905
HPRD
IMGT
MGI ID MGI:1928899
MGI Symbol Tacc2
EMBL AC145294 AC175034
GenPept
RNA Seq Atlas 57752

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca