Version 5.4
Mus musculus Gene: Krt10
Summary
InnateDB Gene IDBG-211017.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt10
Gene Name keratin 10
Synonyms D130054E02Rik; K10; K1C1; Krt-1.10; Krt1-10
Species Mus musculus
Ensembl Gene ENSMUSG00000019761
Encoded Proteins
IDBP-211019
keratin 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186395:
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:99385254-99389364
Strand Reverse strand
Band D
Transcripts
ENSMUST00000103131 ENSMUSP00000099420
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 45 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0030216 keratinocyte differentiation
GO:0030855 epithelial cell differentiation
GO:0071277 cellular response to calcium ion
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0016020 membrane
GO:0045095 keratin filament
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186395
View Gene Order
ENSBTAG00000020824
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05150
Staphylococcus aureus infection pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05150
Staphylococcus aureus infection pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2A513
UniProt Splice Variant
Entrez Gene 16661
UniGene Mm.22662 Mm.398963
RefSeq NM_010660
OMIM
CCDS CCDS25380
HPRD
IMGT
MGI ID MGI:96685
MGI Symbol Krt10
EMBL AL591165
GenPept
RNA Seq Atlas 16661

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca