Version 5.4
Mus musculus Gene: Nkx6-2
Summary
InnateDB Gene IDBG-211515.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nkx6-2
Gene Name NK6 homeobox 2
Synonyms Gtx; Nkx6.2
Species Mus musculus
Ensembl Gene ENSMUSG00000041309
Encoded Proteins
IDBP-211517
NK6 homeobox 2
IDBP-269483
NK6 homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148826:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:139579376-139582797
Strand Reverse strand
Band F4
Transcripts
ENSMUST00000097974 ENSMUSP00000095588
ENSMUST00000106095 ENSMUSP00000101701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0010454 negative regulation of cell fate commitment
GO:0010455 positive regulation of cell fate commitment
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0022010 central nervous system myelination
GO:0030154 cell differentiation
GO:0031018 endocrine pancreas development
GO:0045686 negative regulation of glial cell differentiation
GO:0045687 positive regulation of glial cell differentiation
GO:0048709 oligodendrocyte differentiation
GO:0050885 neuromuscular process controlling balance
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000148826
View Gene Order
Cross-References
SwissProt
TrEMBL D3Z4R4
UniProt Splice Variant
Entrez Gene 14912
UniGene Mm.476889
RefSeq NM_183248
OMIM
CCDS CCDS40170
HPRD
IMGT
MGI ID MGI:1352738
MGI Symbol Nkx6-2
EMBL AC112670 CH466531
GenPept EDL17860
RNA Seq Atlas 14912

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca