Version 5.4
Mus musculus Gene: Dhx35
Summary
InnateDB Gene IDBG-211588.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhx35
Gene Name DEAH (Asp-Glu-Ala-His) box polypeptide 35
Synonyms 1200009D07Rik; Ddx35
Species Mus musculus
Ensembl Gene ENSMUSG00000027655
Encoded Proteins
IDBP-211590
DEAH (Asp-Glu-Ala-His) box polypeptide 35
IDBP-262305
DEAH (Asp-Glu-Ala-His) box polypeptide 35
IDBP-540164
DEAH (Asp-Glu-Ala-His) box polypeptide 35
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101452:
DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:158794807-158858214
Strand Forward strand
Band H1
Transcripts
ENSMUST00000029186 ENSMUSP00000029186
ENSMUST00000109478 ENSMUSP00000105104
ENSMUST00000145692
ENSMUST00000146797
ENSMUST00000156893 ENSMUSP00000119497
ENSMUST00000148359
ENSMUST00000133720
ENSMUST00000157070
ENSMUST00000143195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0008150 biological_process
Cellular Component
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101452
View Gene Order
ENSBTAG00000004039
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.315652
RefSeq NM_001291144 NM_145742 XM_006500188
OMIM
CCDS CCDS16993
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca