Version 5.4
Mus musculus Gene: Ifitm1
Summary
InnateDB Gene IDBG-211937.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ifitm1
Gene Name interferon induced transmembrane protein 1
Synonyms 1110036C17Rik; DSPA2a; Mil-2; Mil2
Species Mus musculus
Ensembl Gene ENSMUSG00000025491
Encoded Proteins
IDBP-211939
interferon induced transmembrane protein 1
IDBP-269591
interferon induced transmembrane protein 1
IDBP-269593
interferon induced transmembrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:140967221-140969825
Strand Forward strand
Band F5
Transcripts
ENSMUST00000026564 ENSMUSP00000026564
ENSMUST00000106042 ENSMUSP00000101657
ENSMUST00000106040 ENSMUSP00000101655
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001503 ossification
GO:0001756 somitogenesis
GO:0008285 negative regulation of cell proliferation
GO:0009607 response to biotic stimulus
GO:0009615 response to virus
GO:0009952 anterior/posterior pattern specification
GO:0030336 negative regulation of cell migration
GO:0034341 response to interferon-gamma
GO:0035455 response to interferon-alpha
GO:0035456 response to interferon-beta
GO:0045071 negative regulation of viral genome replication
GO:0045669 positive regulation of osteoblast differentiation
GO:0046597 negative regulation of viral entry into host cell
GO:0051607 defense response to virus
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_202937
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_230745
Immune System pathway
REACT_229531
Adaptive Immune System pathway
KEGG
mmu04662
B cell receptor signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9D103
TrEMBL
UniProt Splice Variant
Entrez Gene 68713
UniGene Mm.403369 Mm.488865
RefSeq NM_001112715 NM_026820 XM_006536238
OMIM
CCDS CCDS21995
HPRD
IMGT
MGI ID MGI:1915963
MGI Symbol Ifitm1
EMBL AK004121 AK169960 BC027285 BC090258 BC090972 BK001123 CH466531
GenPept AAH27285 AAH90258 AAH90972 BAB23181 BAE41483 DAA01238 EDL17976
RNA Seq Atlas 68713

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca