Version 5.4
Mus musculus Gene: Ifitm3
Summary
InnateDB Gene IDBG-211940.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ifitm3
Gene Name interferon induced transmembrane protein 3
Synonyms 1110004C05Rik; Cd225; Cdw217; DSPA2b; Fgls; IP15; mil-1
Species Mus musculus
Ensembl Gene ENSMUSG00000025492
Encoded Proteins
IDBP-211942
interferon induced transmembrane protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141009586-141010770
Strand Reverse strand
Band F5
Transcripts
ENSMUST00000026565 ENSMUSP00000026565
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007507 heart development
GO:0008285 negative regulation of cell proliferation
GO:0009607 response to biotic stimulus
GO:0009615 response to virus
GO:0046597 negative regulation of viral entry into host cell
GO:0051607 defense response to virus
GO:0055007 cardiac muscle cell differentiation
GO:0060337 type I interferon signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031902 late endosome membrane
GO:0045177 apical part of cell
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_202937
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_230745
Immune System pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9CQW9
TrEMBL
UniProt Splice Variant
Entrez Gene 66141
UniGene
RefSeq NM_025378
OMIM
CCDS CCDS21996
HPRD
IMGT
MGI ID MGI:1913391
MGI Symbol Ifitm3
EMBL AK003407 AK007916 AK007919 AK151890 AY082484 AY594690 BC010291 CH466531
GenPept AAH10291 AAM03316 AAT06089 BAB22771 BAB25347 BAB25350 BAE30774 EDL17977
RNA Seq Atlas 66141

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca