Version 5.4
Mus musculus Gene: Deaf1
Summary
InnateDB Gene IDBG-212128.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Deaf1
Gene Name deformed epidermal autoregulatory factor 1 (Drosophila)
Synonyms AU042387; C230009B13Rik; NUDR
Species Mus musculus
Ensembl Gene ENSMUSG00000058886
Encoded Proteins
IDBP-212130
deformed epidermal autoregulatory factor 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177030:
This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141297176-141327725
Strand Reverse strand
Band F5
Transcripts
ENSMUST00000080553 ENSMUSP00000079395
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001843 neural tube closure
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000177030
View Gene Order
Cross-References
SwissProt Q9Z1T5
TrEMBL
UniProt Splice Variant
Entrez Gene 54006
UniGene Mm.412815
RefSeq NM_016874 XM_006536207
OMIM
CCDS CCDS40185
HPRD
IMGT
MGI ID MGI:1858496
MGI Symbol Deaf1
EMBL AF102818 AK146546 CH466531 FJ377318 FJ377319
GenPept AAC98511 ACN61629 ACN61630 BAE27251 EDL18044
RNA Seq Atlas 54006

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca