Version 5.4
Mus musculus Gene: Brsk2
Summary
InnateDB Gene IDBG-212422.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brsk2
Gene Name BR serine/threonine kinase 2
Synonyms 4833424K13Rik; SAD-A; SADA
Species Mus musculus
Ensembl Gene ENSMUSG00000053046
Encoded Proteins
IDBP-212424
BR serine/threonine kinase 2
IDBP-212426
BR serine/threonine kinase 2
IDBP-212428
BR serine/threonine kinase 2
IDBP-269709
BR serine/threonine kinase 2
IDBP-627278
BR serine/threonine kinase 2
IDBP-627284
BR serine/threonine kinase 2
IDBP-627289
BR serine/threonine kinase 2
IDBP-627290
BR serine/threonine kinase 2
IDBP-627291
BR serine/threonine kinase 2
IDBP-627292
BR serine/threonine kinase 2
IDBP-627293
BR serine/threonine kinase 2
IDBP-627295
BR serine/threonine kinase 2
IDBP-627297
BR serine/threonine kinase 2
IDBP-627299
BR serine/threonine kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174672:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141949751-142004247
Strand Forward strand
Band F5
Transcripts
ENSMUST00000018971 ENSMUSP00000018971
ENSMUST00000075528 ENSMUSP00000074969
ENSMUST00000078200 ENSMUSP00000077330
ENSMUST00000105989 ENSMUSP00000101610
ENSMUST00000172652 ENSMUSP00000133438
ENSMUST00000174405 ENSMUSP00000134289
ENSMUST00000174499 ENSMUSP00000134201
ENSMUST00000172967 ENSMUSP00000133750
ENSMUST00000173924 ENSMUSP00000134153
ENSMUST00000173705 ENSMUSP00000134170
ENSMUST00000174309 ENSMUSP00000134310
ENSMUST00000174237 ENSMUSP00000134566
ENSMUST00000173313 ENSMUSP00000133868
ENSMUST00000173285
ENSMUST00000173330
ENSMUST00000173941 ENSMUSP00000133296
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019901 protein kinase binding
GO:0050321 tau-protein kinase activity
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0006468 protein phosphorylation
GO:0006887 exocytosis
GO:0007067 mitotic nuclear division
GO:0007409 axonogenesis
GO:0018105 peptidyl-serine phosphorylation
GO:0030010 establishment of cell polarity
GO:0030182 neuron differentiation
GO:0031532 actin cytoskeleton reorganization
GO:0048812 neuron projection morphogenesis
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174672
View Gene Order
ENSBTAG00000017861
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.411446 Mm.482784
RefSeq NM_001009929 NM_001009930 NM_029426
OMIM
CCDS CCDS22021 CCDS22022 CCDS22023
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca