Version 5.4
Mus musculus Gene: Nsf
Summary
InnateDB Gene IDBG-213066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nsf
Gene Name N-ethylmaleimide sensitive fusion protein
Synonyms AI316878; AU020090; AU067812; SKD2
Species Mus musculus
Ensembl Gene ENSMUSG00000034187
Encoded Proteins
IDBP-213068
N-ethylmaleimide sensitive fusion protein
IDBP-620248
N-ethylmaleimide sensitive fusion protein
IDBP-620249
N-ethylmaleimide sensitive fusion protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073969:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:103821782-103954056
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000103075 ENSMUSP00000099364
ENSMUST00000040443
ENSMUST00000107009
ENSMUST00000146036
ENSMUST00000127813
ENSMUST00000150516
ENSMUST00000145126
ENSMUST00000140394
ENSMUST00000133774 ENSMUSP00000133591
ENSMUST00000149642 ENSMUSP00000133603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 49 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017075 syntaxin-1 binding
GO:0017111 nucleoside-triphosphatase activity
GO:0019905 syntaxin binding
GO:0030165 PDZ domain binding
GO:0032403 protein complex binding
GO:0042623 ATPase activity, coupled
GO:0046872 metal ion binding
Biological Process
GO:0001921 positive regulation of receptor recycling
GO:0006200 ATP catabolic process
GO:0006813 potassium ion transport
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000073969
View Gene Order
ENSBTAG00000008442
Not yet available
Pathways
NETPATH
REACTOME
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_232605
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
REACT_259290
Neuronal System pathway
REACT_253367
Trafficking of GluR2-containing AMPA receptors pathway
REACT_244428
Trafficking of AMPA receptors pathway
REACT_233318
Transmission across Chemical Synapses pathway
KEGG
mmu04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18422
Trafficking of GluR2-containing AMPA receptors pathway
REACT_18307
Trafficking of AMPA receptors pathway
REACT_13685
Neuronal System pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_18347
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
KEGG
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_008740
OMIM
CCDS CCDS25524
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca