Version 5.4
Homo sapiens Gene: SLC5A11
Summary
InnateDB Gene IDBG-21339.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A11
Gene Name solute carrier family 5 (sodium/glucose cotransporter), member 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158865
Encoded Proteins
IDBP-21341
solute carrier family 5 (sodium/glucose cotransporter), member 11
IDBP-373162
solute carrier family 5 (sodium/glucose cotransporter), member 11
IDBP-373165
solute carrier family 5 (sodium/glucose cotransporter), member 11
IDBP-753180
IDBP-592259
solute carrier family 5 (sodium/glucose cotransporter), member 11
IDBP-754127
IDBP-754681
IDBP-749426
IDBP-754045
IDBP-751908
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:24845841-24911628
Strand Forward strand
Band p12.1
Transcripts
ENST00000347898 ENSP00000289932
ENST00000424767 ENSP00000416782
ENST00000449109 ENSP00000389606
ENST00000488922 ENSP00000458806
ENST00000545376 ENSP00000441384
ENST00000567758 ENSP00000454401
ENST00000565769 ENSP00000457179
ENST00000564125
ENST00000569520 ENSP00000454732
ENST00000568579 ENSP00000456234
ENST00000569071 ENSP00000456376
ENST00000565586
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0006915 apoptotic process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030769
View Gene Order
ENSBTAG00000003467
Not yet available
Pathways
NETPATH
REACTOME
REACT_19188
Inositol transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.164118 Hs.741965
RefSeq NM_001258411 NM_001258412 NM_001258413 NM_001258414 NM_052944 XM_005255080 XM_005255082
HUGO
OMIM
CCDS CCDS10625 CCDS58437 CCDS58438 CCDS58439 CCDS58440
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca