InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rgs9

Summary

InnateDB Gene

IDBG-213785.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rgs9

Gene Name

regulator of G-protein signaling 9

Synonyms

RGS9-1; Rgs9-2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020599

Encoded Proteins

IDBP-213787

regulator of G-protein signaling 9

IDBP-213789

regulator of G-protein signaling 9

IDBP-268216

regulator of G-protein signaling 9

IDBP-268218

regulator of G-protein signaling 9

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108370:
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:109225355-109298129

Strand

Reverse strand

Band

Transcripts

ENSMUST00000020920	ENSMUSP00000020920
ENSMUST00000103062	ENSMUSP00000099351
ENSMUST00000106706	ENSMUSP00000102317
ENSMUST00000106704	ENSMUSP00000102315
ENSMUST00000156785

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005096	GTPase activator activity
GO:0032403	protein complex binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007212	dopamine receptor signaling pathway
GO:0007399	nervous system development
GO:0007601	visual perception
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0035556	intracellular signal transduction
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043547	positive regulation of GTPase activity
GO:0043627	response to estrogen