Version 5.4
Mus musculus Gene: Ogfr
Summary
InnateDB Gene IDBG-213847.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ogfr
Gene Name opioid growth factor receptor
Synonyms 2010013E17Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000049401
Encoded Proteins
IDBP-213851
opioid growth factor receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000060491:
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:180589245-180595836
Strand Forward strand
Band H4
Transcripts
ENSMUST00000029087 ENSMUSP00000029087
ENSMUST00000147070
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0040008 regulation of growth
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000060491
View Gene Order
ENSBTAG00000031718
Not yet available
Cross-References
SwissProt Q99PG2
TrEMBL
UniProt Splice Variant
Entrez Gene 72075
UniGene Mm.250418
RefSeq NM_031373
OMIM
CCDS CCDS17179
HPRD
IMGT
MGI ID MGI:1919325
MGI Symbol Ogfr
EMBL AF303894 AL669926 BC003875
GenPept AAH03875 AAK01353 CAM26816
RNA Seq Atlas 72075

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca