InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ogfr

Summary

InnateDB Protein

IDBP-213851.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ogfr

Protein Name

opioid growth factor receptor

Synonyms

2010013E17Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029087

InnateDB Gene

IDBG-213847 (Ogfr)

Protein Structure

UniProt Annotation

Function

Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=The OGF/OGFR complex is probably translocated to the nucleus.

Disease Associations

Tissue Specificity

Expressed in all tissues examined, including brain, heart, lung, liver, kidney and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity

Biological Process

GO:0040008

regulation of growth

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1919325

InterPro

IPR006757 Opioid growth factor receptor (OGFr) conserved domain

PFAM

PF04664

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99PG2

PhosphoSite

PhosphoSite-Q99PG2

TrEMBL

UniProt Splice Variant

Entrez Gene

72075

UniGene

Mm.250418

RefSeq

NP_113550

MGI ID

MGI Symbol

Ogfr

OMIM

CCDS

CCDS17179

HPRD

IMGT

EMBL

AF303894 AL669926 BC003875

GenPept

AAH03875 AAK01353 CAM26816