Mus musculus Gene: Ttyh2
Summary
InnateDB Gene IDBG-214102.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttyh2
Gene Name tweety homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034714
Encoded Proteins
tweety homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141540:
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:114675431-114720977
Strand Forward strand
Band E2
Transcripts
ENSMUST00000045779 ENSMUSP00000037821
ENSMUST00000141111
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005254 chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0034707 chloride channel complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Orphan transporters pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271934 Mm.475167
RefSeq NM_053273
OMIM
CCDS CCDS25608
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas