Version 5.4
Mus musculus Protein: Ttyh2
Summary
InnateDB Protein IDBP-214104.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttyh2
Protein Name tweety homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037821
InnateDB Gene IDBG-214102 (Ttyh2)
Protein Structure
UniProt Annotation
Function Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005254 chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0034707 chloride channel complex
Protein Structure and Domains
PDB ID MGI:2157091
InterPro IPR006990 Tweety
PFAM PF04906
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3TH73
PhosphoSite PhosphoSite-Q3TH73
TrEMBL
UniProt Splice Variant
Entrez Gene 117160
UniGene Mm.475167
RefSeq NP_444503
MGI ID
MGI Symbol Ttyh2
OMIM
CCDS CCDS25608
HPRD
IMGT
EMBL AF329682 AK152172 AK155166 AK156393 AK168408 AL645484 AL663079 BC060740
GenPept AAH60740 AAL16785 BAE31004 BAE33089 BAE33698 BAE40325 CAM19258 CAM22870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca