Version 5.4
Mus musculus Gene: Dnaic2
Summary
InnateDB Gene IDBG-214115.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnaic2
Gene Name dynein, axonemal, intermediate chain 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034706
Encoded Proteins
IDBP-214117
dynein, axonemal, intermediate chain 2
IDBP-214119
dynein, axonemal, intermediate chain 2
IDBP-541376
dynein, axonemal, intermediate chain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171595:
The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:114727408-114757889
Strand Forward strand
Band E2
Transcripts
ENSMUST00000092469 ENSMUSP00000090126
ENSMUST00000069325 ENSMUSP00000065787
ENSMUST00000151053
ENSMUST00000136403
ENSMUST00000141762 ENSMUSP00000114700
ENSMUST00000144872
ENSMUST00000130692
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
GO:0042384 cilium assembly
Cellular Component
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0005930 axoneme
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171595
View Gene Order
ENSBTAG00000016732
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt A2AC93
TrEMBL R4GML5
UniProt Splice Variant
Entrez Gene 432611
UniGene Mm.212764
RefSeq NM_001034878 XM_006533660 XM_006533661 XM_006533662
OMIM
CCDS CCDS36366
HPRD
IMGT
MGI ID MGI:2685574
MGI Symbol Dnaic2
EMBL AL663079 CH466558 EF565270
GenPept ABU62629 CAM19252 CAM19253 EDL34441
RNA Seq Atlas 432611

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca