Version 5.4
Mus musculus Gene: Cd300a
Summary
InnateDB Gene IDBG-214150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd300a
Gene Name CD300A antigen
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034652
Encoded Proteins
IDBP-214152
CD300A antigen
IDBP-268470
CD300A antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 22043923
Cd300a inhibits Myd88 and/or TRIF-mediated TLR signalling pathway through activation of Ptpn6. (Demonstrated in human)
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:114890041-114904654
Strand Forward strand
Band E2
Transcripts
ENSMUST00000045151 ENSMUSP00000036773
ENSMUST00000106582 ENSMUSP00000102192
ENSMUST00000153245
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0002552 serotonin secretion by mast cell
GO:0006898 receptor-mediated endocytosis
GO:0014063 negative regulation of serotonin secretion
GO:0043305 negative regulation of mast cell degranulation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0042629 mast cell granule
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.294439 Mm.448323
RefSeq NM_170758
OMIM
CCDS CCDS25613
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca