Version 5.4
Mus musculus Gene: Tsen54
Summary
InnateDB Gene IDBG-214357.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tsen54
Gene Name tRNA splicing endonuclease 54 homolog (S. cerevisiae)
Synonyms 0610034P02Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000020781
Encoded Proteins
IDBP-214359
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
IDBP-268678
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
IDBP-539799
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
IDBP-531778
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
IDBP-541344
tRNA splicing endonuclease 54 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182173:
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115814724-115823094
Strand Forward strand
Band E2
Transcripts
ENSMUST00000021134 ENSMUSP00000021134
ENSMUST00000106481 ENSMUSP00000102090
ENSMUST00000129765
ENSMUST00000141748
ENSMUST00000128266
ENSMUST00000136343 ENSMUSP00000120506
ENSMUST00000154304 ENSMUSP00000116955
ENSMUST00000157061 ENSMUSP00000118342
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006397 mRNA processing
Cellular Component
GO:0005575 cellular_component
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182173
View Gene Order
ENSBTAG00000000824
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275438
RefSeq NM_029557 XM_006534415 XM_006534416 XM_006534417 XM_006534420
OMIM
CCDS CCDS25648
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca