Version 5.4
Mus musculus Gene: Sept9
Summary
InnateDB Gene IDBG-214554.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sept9
Gene Name septin 9
Synonyms Msf; MSF1; PNUTL4; Sint1
Species Mus musculus
Ensembl Gene ENSMUSG00000059248
Encoded Proteins
IDBP-214556
septin 9
IDBP-214558
septin 9
IDBP-214560
septin 9
IDBP-268941
septin 9
IDBP-268947
septin 9
IDBP-539671
septin 9
IDBP-542010
septin 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184640:
This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:117199661-117362325
Strand Forward strand
Band E2
Transcripts
ENSMUST00000093907 ENSMUSP00000091435
ENSMUST00000019038 ENSMUSP00000019038
ENSMUST00000100193 ENSMUSP00000097767
ENSMUST00000106354 ENSMUSP00000101961
ENSMUST00000106349 ENSMUSP00000101956
ENSMUST00000153668 ENSMUSP00000120382
ENSMUST00000127383 ENSMUSP00000120065
ENSMUST00000155331
ENSMUST00000134852
ENSMUST00000129387
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051291 protein heterooligomerization
GO:0051301 cell division
Cellular Component
GO:0001725 stress fiber
GO:0005874 microtubule
GO:0015629 actin cytoskeleton
GO:0031105 septin complex
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184640
View Gene Order
ENSBTAG00000002633
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt Q80UG5
TrEMBL A8Y5D3
UniProt Splice Variant
Entrez Gene 53860
UniGene Mm.38450 Mm.451420
RefSeq NM_017380 NM_001113486 NM_001113487 NM_001113488 XM_006533744 XM_006533745 XM_006533746
OMIM
CCDS CCDS25684 CCDS48990 CCDS48991
HPRD
IMGT
MGI ID MGI:1858222
MGI Symbol Sept9
EMBL AF450141 AF450142 AJ250723 AK031757 AK122415 AK141312 AL603868 AL611935 AL645975 BC046524
GenPept AAH46524 AAL50685 BAC27538 BAC65697 BAE24646 CAB59833 CAM13312 CAM15613 CAM19703
RNA Seq Atlas 53860

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca