Version 5.4
Mus musculus Gene: Tmc6
Summary
InnateDB Gene IDBG-214573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmc6
Gene Name transmembrane channel-like gene family 6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025572
Encoded Proteins
IDBP-214575
transmembrane channel-like gene family 6
IDBP-214577
transmembrane channel-like gene family 6
IDBP-534836
transmembrane channel-like gene family 6
IDBP-541574
transmembrane channel-like gene family 6
IDBP-533122
transmembrane channel-like gene family 6
IDBP-541021
transmembrane channel-like gene family 6
IDBP-536207
transmembrane channel-like gene family 6
IDBP-542734
transmembrane channel-like gene family 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141524:
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:117765988-117782198
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026659 ENSMUSP00000026659
ENSMUST00000103025 ENSMUSP00000099314
ENSMUST00000131606 ENSMUSP00000123264
ENSMUST00000148220
ENSMUST00000149589 ENSMUSP00000116521
ENSMUST00000143406 ENSMUSP00000117566
ENSMUST00000136729 ENSMUSP00000118068
ENSMUST00000152304 ENSMUSP00000122495
ENSMUST00000127227 ENSMUSP00000116613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141524
View Gene Order
ENSBTAG00000018661
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.286963 Mm.446455
RefSeq NM_145439 NM_181321 XM_006533112 XM_006533113 XM_006533114 XM_006533115 XM_006533116 XM_006533117 XM_006533121
OMIM
CCDS CCDS25687 CCDS25688
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca