Version 5.4
Mus musculus Gene: Arhgdia
Summary
InnateDB Gene IDBG-214842.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgdia
Gene Name Rho GDP dissociation inhibitor (GDI) alpha
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025132
Encoded Proteins
IDBP-214844
Rho GDP dissociation inhibitor (GDI) alpha
IDBP-269273
Rho GDP dissociation inhibitor (GDI) alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120578104-120581624
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000067936 ENSMUSP00000063714
ENSMUST00000106197 ENSMUSP00000101803
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0030336 negative regulation of cell migration
GO:0032880 regulation of protein localization
GO:0043547 positive regulation of GTPase activity
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0001772 immunological synapse
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_222662
p75NTR regulates axonogenesis pathway
REACT_203657
Axonal growth inhibition (RHOA activation) pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_214242
Axonal growth stimulation pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
KEGG
mmu04722
Neurotrophin signaling pathway pathway
mmu04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_133796 XM_006532549
OMIM
CCDS CCDS25743
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca