Version 5.4
Mus musculus Gene: Mafg
Summary
InnateDB Gene IDBG-214862.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mafg
Gene Name v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
Synonyms AA545192; C630022N07Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000051510
Encoded Proteins
IDBP-214864
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
IDBP-269302
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
IDBP-269304
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
IDBP-269306
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197063:
Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120625117-120633600
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000058162 ENSMUSP00000053899
ENSMUST00000106182 ENSMUSP00000101788
ENSMUST00000106181 ENSMUSP00000101787
ENSMUST00000106180 ENSMUSP00000101786
ENSMUST00000128498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0001701 in utero embryonic development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030534 adult behavior
GO:0030641 regulation of cellular pH
GO:0042127 regulation of cell proliferation
GO:0045604 regulation of epidermal cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197063
View Gene Order
ENSBTAG00000000040
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
KEGG
INOH
PID NCI
ap1_pathway
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.268010 Mm.292957 Mm.393664 Mm.486526
RefSeq NM_010756 XM_006532395
OMIM
CCDS CCDS25748
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca