Version 5.4
Mus musculus Gene: Cbr2
Summary
InnateDB Gene IDBG-214896.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cbr2
Gene Name carbonyl reductase 2
Synonyms MLCR
Species Mus musculus
Ensembl Gene ENSMUSG00000025150
Encoded Proteins
IDBP-214898
carbonyl reductase 2
IDBP-538867
carbonyl reductase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120729489-120732114
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026148 ENSMUSP00000026148
ENSMUST00000154479
ENSMUST00000154565 ENSMUSP00000117739
ENSMUST00000149450
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004090 carbonyl reductase (NADPH) activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0043621 protein self-association
GO:0050662 coenzyme binding
Biological Process
GO:0006116 NADH oxidation
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0051262 protein tetramerization
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu00590
Arachidonic acid metabolism pathway
mmu00980
Metabolism of xenobiotics by cytochrome P450 pathway
INOH
PID NCI
Cross-References
SwissProt P08074
TrEMBL Q542P5
UniProt Splice Variant
Entrez Gene 12409
UniGene
RefSeq NM_007621
OMIM
CCDS CCDS25756
HPRD
IMGT
MGI ID MGI:107200
MGI Symbol Cbr2
EMBL AK081816 BC010758 CH466558 D26123 X07411
GenPept AAH10758 BAA05120 BAC38340 CAA30309 EDL34801
RNA Seq Atlas 12409

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca