InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Csnk1d

Summary

InnateDB Gene

IDBG-214925.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Csnk1d

Gene Name

casein kinase 1, delta

Synonyms

1200006A05Rik; AA409348; D930010H05Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000025162

Encoded Proteins

IDBP-214929

casein kinase 1, delta

IDBP-214931

casein kinase 1, delta

IDBP-538790

casein kinase 1, delta

IDBP-538540

casein kinase 1, delta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the casein kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and hedgehog signaling pathways. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:120961749-120991330

Strand

Reverse strand

Band

Transcripts

ENSMUST00000018274	ENSMUSP00000018274
ENSMUST00000070575	ENSMUSP00000070721
ENSMUST00000131375
ENSMUST00000141071
ENSMUST00000139267
ENSMUST00000154483	ENSMUSP00000117472
ENSMUST00000146837	ENSMUSP00000115055
ENSMUST00000155070

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042277	peptide binding
GO:0050321	tau-protein kinase activity
GO:0051219	phosphoprotein binding

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0006468	protein phosphorylation
GO:0016055	Wnt signaling pathway
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032922	circadian regulation of gene expression
GO:0042752	regulation of circadian rhythm
GO:0051225	spindle assembly
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005819	spindle
GO:0005829	cytosol
GO:0005876	spindle microtubule
GO:0005886	plasma membrane
GO:0048471	perinuclear region of cytoplasm