Version 5.4
Mus musculus Gene: Gspt2
Summary
InnateDB Gene IDBG-215352.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gspt2
Gene Name G1 to S phase transition 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000071723
Encoded Proteins
IDBP-252928
G1 to S phase transition 2
IDBP-790047
G1 to S phase transition 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189369:
This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:94636069-94643244
Strand Forward strand
Band C3
Transcripts
ENSMUST00000096368 ENSMUSP00000109523
ENSMUST00000137033 ENSMUSP00000139286
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006184 GTP catabolic process
GO:0006412 translation
GO:0007049 cell cycle
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000189369
View Gene Order
Pathways
NETPATH
REACTOME
REACT_254308
Translation pathway
REACT_231519
Eukaryotic Translation Termination pathway
REACT_198522
Nonsense-Mediated Decay (NMD) pathway
REACT_247926
Metabolism of proteins pathway
REACT_198528
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_198524
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_233572
Gene Expression pathway
KEGG
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75768
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_75822
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_1986
Eukaryotic Translation Termination pathway
REACT_75886
Nonsense-Mediated Decay (NMD) pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q149F3
TrEMBL
UniProt Splice Variant
Entrez Gene 14853
UniGene Mm.20826 Mm.487061
RefSeq NM_008179
OMIM
CCDS CCDS41064
HPRD
IMGT
MGI ID MGI:1316727
MGI Symbol Gspt2
EMBL AB003503 AK019241 AL645466 BC117825 BC117826
GenPept AAI17826 AAI17827 BAA32527 BAB31621 CAM15955
RNA Seq Atlas 14853

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca