Version 5.4
Homo sapiens Gene: AEBP2
Summary
InnateDB Gene IDBG-22258.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AEBP2
Gene Name AE binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139154
Encoded Proteins
IDBP-22260
AE binding protein 2
IDBP-22262
AE binding protein 2
IDBP-232047
AE binding protein 2
IDBP-232383
AE binding protein 2
IDBP-585027
AE binding protein 2
IDBP-583409
AE binding protein 2
IDBP-592810
AE binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:19404045-19720801
Strand Forward strand
Band p12.3
Transcripts
ENST00000360995 ENSP00000354267
ENST00000266508 ENSP00000266508
ENST00000398864 ENSP00000381840
ENST00000398731 ENSP00000381715
ENST00000512223 ENSP00000445587
ENST00000538425 ENSP00000444255
ENST00000541908 ENSP00000437983
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
Cellular Component
GO:0005634 nucleus
GO:0035098 ESC/E(Z) complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030232
View Gene Order
ENSBTAG00000010818
Not yet available
Pathways
NETPATH
REACTOME
REACT_200808
PRC2 methylates histones and DNA pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F5GZR7 G5EA50
UniProt Splice Variant
Entrez Gene 121536
UniGene Hs.126497 Hs.595408
RefSeq NM_001114176 NM_001267043 NM_153207
HUGO HGNC:24051
OMIM
CCDS CCDS44841 CCDS44842 CCDS58215
HPRD 16477
IMGT
EMBL AC090059 AC091805 AC137561 CH471094
GenPept EAW96398
RNA Seq Atlas 121536

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca