Version 5.4
Mus musculus Gene: Rab11b
Summary
InnateDB Gene IDBG-225619.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab11b
Gene Name RAB11B, member RAS oncogene family
Synonyms A730055L17Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000077450
Encoded Proteins
IDBP-251892
RAB11B, member RAS oncogene family
IDBP-626577
RAB11B, member RAS oncogene family
IDBP-626579
RAB11B, member RAS oncogene family
IDBP-626580
RAB11B, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185236:
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:33742484-33760530
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000057373 ENSMUSP00000110021
ENSMUST00000173860 ENSMUSP00000134448
ENSMUST00000172894 ENSMUSP00000134544
ENSMUST00000173987 ENSMUSP00000133921
ENSMUST00000174744
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0001881 receptor recycling
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0032402 melanosome transport
GO:0033572 transferrin transport
GO:0035773 insulin secretion involved in cellular response to glucose stimulus
GO:0044070 regulation of anion transport
GO:0045054 constitutive secretory pathway
GO:0045055 regulated secretory pathway
GO:0071468 cellular response to acidity
GO:1990126 retrograde transport, endosome to plasma membrane
GO:2000008 regulation of protein localization to cell surface
GO:2001135 regulation of endocytic recycling
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030054 cell junction
GO:0030670 phagocytic vesicle membrane
GO:0030672 synaptic vesicle membrane
GO:0045335 phagocytic vesicle
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185236
View Gene Order
ENSBTAG00000002475
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
mmu04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Cross-References
SwissProt P46638
TrEMBL G3UY29 G3UZD3 Q78ZJ8
UniProt Splice Variant
Entrez Gene 19326
UniGene Mm.387587
RefSeq NM_008997 XM_006523887 XM_006536572 XM_006537304
OMIM
CCDS CCDS28628
HPRD
IMGT
MGI ID MGI:99425
MGI Symbol Rab11b
EMBL AB232606 AF528162 AK146452 AK146460 AK146623 AK146978 AK147077 AK148022 AK148106 BC054753 BC085270 BC157916 CH466660 CT030732 L26528
GenPept AAC42093 AAH54753 AAH85270 AAI57917 AAO17377 BAE27183 BAE27188 BAE27312 BAE27582 BAE27658 BAE28293 BAE28347 BAF02868 EDL10205 EDL10206
RNA Seq Atlas 19326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca