Version 5.4
| Homo sapiens Gene: CDCA4 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-22970.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | CDCA4 | ||||||||||||||||||
| Gene Name | cell division cycle associated 4 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000170779 | ||||||||||||||||||
| Encoded Proteins |
cell division cycle associated 4
cell division cycle associated 4
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, Sep 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 14:105009573-105021148 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q32.33 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||
| SwissProt | Q9BXL8 | ||||||||||||||||||
| TrEMBL | A0A024R6P3 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 55038 | ||||||||||||||||||
| UniGene | Hs.34045 | ||||||||||||||||||
| RefSeq | NM_145701 NM_017955 | ||||||||||||||||||
| HUGO | HGNC:14625 | ||||||||||||||||||
| OMIM | 612270 | ||||||||||||||||||
| CCDS | CCDS9996 | ||||||||||||||||||
| HPRD | 13015 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF322239 AK000771 BC011736 BC025263 CH471061 | ||||||||||||||||||
| GenPept | AAH11736 AAH25263 AAK31075 BAA91373 EAW81894 EAW81896 EAW81897 | ||||||||||||||||||
| RNA Seq Atlas | 55038 | ||||||||||||||||||