Homo sapiens Protein: CDCA4
Summary
InnateDB Protein IDBP-22972.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDCA4
Protein Name cell division cycle associated 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000337226
InnateDB Gene IDBG-22970 (CDCA4)
Protein Structure
UniProt Annotation
Function May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:16984923}.
Disease Associations
Tissue Specificity Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes. Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon. Hardly detectable, if at all, in the brain, skeletal muscle and heart. {ECO:0000269PubMed:16984923}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009263 SERTA domain
PFAM PF06031
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXL8
PhosphoSite PhosphoSite-Q9BXL8
TrEMBL A0A024R6P3
UniProt Splice Variant
Entrez Gene 55038
UniGene Hs.34045
RefSeq NP_060425
HUGO HGNC:14625
OMIM 612270
CCDS CCDS9996
HPRD 13015
IMGT
EMBL AF322239 AK000771 BC011736 BC025263 CH471061
GenPept AAH11736 AAH25263 AAK31075 BAA91373 EAW81894 EAW81896 EAW81897