Version 5.4
Homo sapiens Gene: ANKRD17
Summary
InnateDB Gene IDBG-23294.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANKRD17
Gene Name ankyrin repeat domain 17
Synonyms GTAR; NY-BR-16
Species Homo sapiens
Ensembl Gene ENSG00000132466
Encoded Proteins
IDBP-23296
ankyrin repeat domain 17
IDBP-23298
ankyrin repeat domain 17
IDBP-483231
ankyrin repeat domain 17
IDBP-594258
ankyrin repeat domain 17
IDBP-603031
ankyrin repeat domain 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23711367
ANKRD17 binds to NOD2 and contributes to inflammatory responses against Shigella flexneri.
Entrez Gene
Summary This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:73073376-73258798
Strand Reverse strand
Band q13.3
Transcripts
ENST00000358602 ENSP00000351416
ENST00000330838 ENSP00000332265
ENST00000509867 ENSP00000427151
ENST00000510127
ENST00000513908
ENST00000514252
ENST00000558247 ENSP00000453434
ENST00000560507
ENST00000561029 ENSP00000453294
ENST00000559367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001955 blood vessel maturation
GO:0016032 viral process
GO:0045087 innate immune response (InnateDB)
GO:0051151 negative regulation of smooth muscle cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055204
View Gene Order
ENSBTAG00000004912
Not yet available
Cross-References
SwissProt O75179
TrEMBL
UniProt Splice Variant
Entrez Gene 26057
UniGene Hs.543573 Hs.644997 Hs.731211 Hs.733994 Hs.743705
RefSeq NM_032217 XM_005265667 NM_001286771 NM_198889 XM_005265671
HUGO HGNC:23575
OMIM
CCDS CCDS34004 CCDS34003 CCDS68721
HPRD 10648
IMGT
EMBL AB014597 AC053527 AC095053 AC105757 AF308285 AK025859 AL831903 BC004173 BC007747 BC019963 BC043394 CH471057
GenPept AAG48253 AAH04173 AAH07747 AAH19963 AAH43394 BAA31672 BAB15260 CAD38571 EAX05655
RNA Seq Atlas 26057

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca