InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ANKRD17

Summary

InnateDB Protein

IDBP-23296.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANKRD17

Protein Name

ankyrin repeat domain 17

Synonyms

GTAR; NY-BR-16;

Species

Homo sapiens

Ensembl Protein

ENSP00000351416

InnateDB Gene

IDBG-23294 (ANKRD17)

Protein Structure

UniProt Annotation

Function

Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification (By similarity). Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease). {ECO:0000250, ECO:0000269PubMed:17276651}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17276651}. Nucleus {ECO:0000269PubMed:17276651}. Note=Detected around the nucleolus.

Disease Associations

Tissue Specificity

Expressed in bone marrow. {ECO:0000269PubMed:17276651}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001955	blood vessel maturation
GO:0016032	viral process
GO:0045087	innate immune response (InnateDB)
GO:0051151	negative regulation of smooth muscle cell differentiation