Version 5.4
Homo sapiens Gene: RNASE3
Summary
InnateDB Gene IDBG-2387.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNASE3
Gene Name ribonuclease, RNase A family, 3
Synonyms ECP; RNS3
Species Homo sapiens
Ensembl Gene ENSG00000169397
Encoded Proteins
IDBP-2389
ribonuclease, RNase A family, 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:20891399-20892348
Strand Forward strand
Band q11.2
Transcripts
ENST00000304639 ENSP00000302324
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004540 ribonuclease activity
GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters
Biological Process
GO:0002227 innate immune response in mucosa
GO:0006401 RNA catabolic process
GO:0019731 antibacterial humoral response
GO:0045087 innate immune response
GO:0050830 defense response to Gram-positive bacterium
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa05310
Asthma pathway
INOH
PID NCI
Cross-References
SwissProt P12724
TrEMBL
UniProt Splice Variant
Entrez Gene 6037
UniGene Hs.73839
RefSeq NM_002935
HUGO HGNC:10046
OMIM 131398
CCDS CCDS9560
HPRD
IMGT
EMBL AF294019 AF294020 AF294021 AF294022 AF294023 AF294024 AF294025 AF294026 AF441204 AF441205 AF441206 AL133371 BC096060 BC096061 BC096062 M28128 X15161 X16545 X55990
GenPept AAA50283 AAG31589 AAG31590 AAG31591 AAG31592 AAG31593 AAG31594 AAG31595 AAG31596 AAH96060 AAH96061 AAH96062 AAL35279 AAL35280 AAL35281 CAA33251 CAA34545 CAA39462
RNA Seq Atlas 6037

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca