Version 5.4
Homo sapiens Gene: RNASE2
Summary
InnateDB Gene IDBG-2396.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNASE2
Gene Name ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
Synonyms EDN; RAF3; RNS2
Species Homo sapiens
Ensembl Gene ENSG00000169385
Encoded Proteins
IDBP-2398
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:20955452-20956436
Strand Forward strand
Band q11.2
Transcripts
ENST00000304625 ENSP00000303276
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004522 pancreatic ribonuclease activity
GO:0004540 ribonuclease activity
Biological Process
GO:0006401 RNA catabolic process
GO:0006935 chemotaxis
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P10153
TrEMBL W0UV60
UniProt Splice Variant
Entrez Gene 6036
UniGene Hs.728
RefSeq NM_002934
HUGO HGNC:10045
OMIM 131410
CCDS CCDS9561
HPRD
IMGT
EMBL AF294007 AF294008 AF294009 AF294010 AF294011 AF294012 AF294013 AF294014 AF294015 BC093678 BC093680 BC096059 CH471078 HG328843 M24157 M28129 M30510 X16546 X55987 X55988
GenPept AAA50284 AAA52337 AAC82505 AAG31577 AAG31578 AAG31579 AAG31580 AAG31581 AAG31582 AAG31583 AAG31584 AAG31585 AAH93678 AAH93680 AAH96059 CAA34546 CAA39459 CAA39460 CDG31919 EAW66435
RNA Seq Atlas 6036

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca