Homo sapiens Gene: CENPK
Summary
InnateDB Gene IDBG-23981.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPK
Gene Name centromere protein K
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000123219
Encoded Proteins
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
centromere protein K
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:65517766-65563171
Strand Reverse strand
Band q12.3
Transcripts
ENST00000242872 ENSP00000242872
ENST00000396679 ENSP00000379911
ENST00000514814 ENSP00000422421
ENST00000508421 ENSP00000421034
ENST00000510693 ENSP00000425686
ENST00000506282
ENST00000509397 ENSP00000424450
ENST00000511841
ENST00000505960 ENSP00000423308
ENST00000515497 ENSP00000422365
ENST00000515873
ENST00000510768 ENSP00000424039
ENST00000513951
ENST00000502997 ENSP00000424686
ENST00000510354 ENSP00000427648
ENST00000504508
ENST00000508311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006334 nucleosome assembly
GO:0034080 centromere-specific nucleosome assembly
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Deposition of new CENPA-containing nucleosomes at the centromere pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Chromosome Maintenance pathway
Nucleosome assembly pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.529778 Hs.663542
RefSeq NM_001267038 NM_022145 XM_006714668
HUGO
OMIM
CCDS CCDS3984
HPRD 13323
IMGT
EMBL
GenPept
RNA Seq Atlas