Homo sapiens Gene: RCN2
Summary
InnateDB Gene IDBG-24088.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol RCN2
Gene Name reticulocalbin 2, EF-hand calcium binding domain
Synonyms E6BP; ERC-55; ERC55; TCBP49;
Species Homo sapiens
Ensembl Gene ENSG00000117906
Encoded Proteins
reticulocalbin 2, EF-hand calcium binding domain
reticulocalbin 2, EF-hand calcium binding domain
reticulocalbin 2, EF-hand calcium binding domain
reticulocalbin 2, EF-hand calcium binding domain
Protein Structure
Entrez Gene
Summary The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:77223960-77242601
Strand Forward strand
Band q24.3
Transcripts
ENST00000320963 ENSP00000319739
ENST00000394885 ENSP00000378349
ENST00000394883 ENSP00000378347
ENST00000557805 ENSP00000453052
ENST00000558598
ENST00000560833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 37 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q14257
TrEMBL A8MXP8 F8WCY5
UniProt Splice Variant
Entrez Gene 5955
UniGene Hs.79088
RefSeq NM_002902
HUGO 9935
OMIM 602584
CCDS CCDS10291
HPRD 03993
IMGT
EMBL AC051643 AK313833 BC004892 BT009790 X78669
GenPept AAH04892 AAP88792 BAG36566 CAA55343
ImmGen RCN2 (murine)
RNA Seq Atlas 5955