Homo sapiens Gene: RCN2

Summary
InnateDB Gene IDBG-24088.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol RCN2
Gene Name reticulocalbin 2, EF-hand calcium binding domain
Synonyms E6BP; ERC-55; ERC55; TCBP49
Species Homo sapiens
Ensembl Gene ENSG00000117906
Encoded Proteins
IDBP-24090 reticulocalbin 2, EF-hand calcium binding domain
IDBP-240670 reticulocalbin 2, EF-hand calcium binding domain
IDBP-240672 reticulocalbin 2, EF-hand calcium binding domain
IDBP-601899 reticulocalbin 2, EF-hand calcium binding domain
Entrez Gene
Summary The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15: 77223960-77242601
Strand Forward strand
Band q24.3
Transcripts
ENST00000320963  ENSP00000319739
ENST00000394885  ENSP00000378349
ENST00000394883  ENSP00000378347
ENST00000557805  ENSP00000453052
ENST00000558598 
ENST00000560833 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein‑Protein  23
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Predicted by orthology
Total 3 [view]
Gene Ontology
Accession GO Term
Molecular Function
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000032320 Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
ENSBTAG00000015780 Not yet available Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q14257 
TrEMBL A8MXP8 F8WCY5
UniProt Splice Variant
Entrez Gene 5955 
UniGene Hs.79088
RefSeq NM_002902 
HUGO 9935 
OMIM 602584
CCDS CCDS10291 
HPRD 03993
IMGT
EMBL AC051643 AK313833 BC004892 BT009790 X78669
GenPept AAH04892  AAP88792  BAG36566  CAA55343 
ImmGen RCN2 (murine) 
RNA Seq Atlas 5955