Version 5.4
Homo sapiens Gene: TSPAN3
Summary
InnateDB Gene IDBG-24194.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN3
Gene Name tetraspanin 3
Synonyms TM4-A; TM4SF8; TSPAN-3
Species Homo sapiens
Ensembl Gene ENSG00000140391
Encoded Proteins
IDBP-24196
tetraspanin 3
IDBP-24198
tetraspanin 3
IDBP-378325
tetraspanin 3
IDBP-586216
tetraspanin 3
IDBP-601313
tetraspanin 3
IDBP-592243
tetraspanin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:77041404-77083984
Strand Reverse strand
Band q24.3
Transcripts
ENST00000267970 ENSP00000267970
ENST00000346495 ENSP00000341329
ENST00000424443 ENSP00000407243
ENST00000560715
ENST00000561277 ENSP00000453613
ENST00000559494 ENSP00000452835
ENST00000558745 ENSP00000453868
ENST00000558394
ENST00000560514
ENST00000559373
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032324
View Gene Order
ENSBTAG00000002415
Not yet available
Cross-References
SwissProt
TrEMBL H0YMH8
UniProt Splice Variant
Entrez Gene 10099
UniGene Hs.5062 Hs.741445
RefSeq NM_001168412 NM_005724 NM_198902
HUGO HGNC:17752
OMIM 613134
CCDS CCDS10292 CCDS10293 CCDS53963
HPRD 15512
IMGT
EMBL AC090181
GenPept
RNA Seq Atlas 10099

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca