Version 5.4
| Homo sapiens Gene: MAGEA12 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-242743.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | MAGEA12 | ||||||||||||||||||
| Gene Name | melanoma antigen family A, 12 | ||||||||||||||||||
| Synonyms | CT1.12; MAGE12 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000213401 | ||||||||||||||||||
| Encoded Proteins |
melanoma antigen family A, 12
melanoma antigen family A, 12
melanoma antigen family A, 12
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009] This gene is closely related to several other genes clustered on chromosome X. These genes may be overexpressed in tumors. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq, Jun 2014] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome X:152733779-152737669 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q28 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | P43365 | ||||||||||||||||||
| TrEMBL | Q6FHH8 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 4111 | ||||||||||||||||||
| UniGene | Hs.169246 | ||||||||||||||||||
| RefSeq | NM_001166386 NM_001166387 NM_005367 | ||||||||||||||||||
| HUGO | HGNC:6799 | ||||||||||||||||||
| OMIM | 300177 | ||||||||||||||||||
| CCDS | CCDS76048 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AK314168 BC003408 BT007108 CH471169 CR541775 L18877 U82671 | ||||||||||||||||||
| GenPept | AAA19023 AAH03408 AAP35772 BAG36852 CAG46574 EAW99432 | ||||||||||||||||||
| RNA Seq Atlas | 4111 | ||||||||||||||||||