Version 5.4
Homo sapiens Protein: MAGEA12
Summary
InnateDB Protein IDBP-242700.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEA12
Protein Name melanoma antigen family A, 12
Synonyms CT1.12; MAGE12;
Species Homo sapiens
Ensembl Protein ENSP00000377478
InnateDB Gene IDBG-242743 (MAGEA12)
Protein Structure
UniProt Annotation
Function Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines. {ECO:0000269PubMed:17942928}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR002190 MAGE protein
IPR021072 Melanoma associated antigen, MAGE, N-terminal
PFAM PF01454
PF12440
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43365
PhosphoSite PhosphoSite-P43365
TrEMBL Q6FHH8
UniProt Splice Variant
Entrez Gene 4111
UniGene Hs.169246
RefSeq NP_001159858
HUGO HGNC:6799
OMIM 300177
CCDS CCDS76048
HPRD 02169
IMGT
EMBL AK314168 BC003408 BT007108 CH471169 CR541775 L18877 U82671
GenPept AAA19023 AAH03408 AAP35772 BAG36852 CAG46574 EAW99432

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca