Version 5.4
Homo sapiens Gene: YBX2
Summary
InnateDB Gene IDBG-24279.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YBX2
Gene Name Y box binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000006047
Encoded Proteins
IDBP-24281
Y box binding protein 2
IDBP-758739
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:7288252-7294615
Strand Reverse strand
Band p13.1
Transcripts
ENST00000007699 ENSP00000007699
ENST00000570720
ENST00000571464 ENSP00000459587
ENST00000571834
ENST00000570627
ENST00000571485
ENST00000571127
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0008289 lipid binding
GO:0043021 ribonucleoprotein complex binding
GO:0045182 translation regulator activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0009386 translational attenuation
GO:0017148 negative regulation of translation
GO:0048255 mRNA stabilization
GO:0048477 oogenesis
GO:0048599 oocyte development
GO:0051100 negative regulation of binding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005844 polysome
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018554
View Gene Order
ENSBTAG00000009126
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567494 Hs.678212
RefSeq NM_015982
HUGO
OMIM
CCDS CCDS11098
HPRD 18311
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca